Moisturization & Hydration Efficacy Evaluation

Creative Biogene Zebrafish Platform, a leading cosmetic efficacy evaluation company with years of experience and knowledge of cosmetics, provides world-class moisturization & hydration efficacy evaluation services to speed up your declaration process. We use advanced techniques and cutting-edge equipment to provide you with accurate and reliable results that will give you an edge in the market. Trust us to deliver top-notch solutions that will exceed your expectations and help you achieve your goals.

As the largest organ of the human body, the skin serves as a barrier between the cells and the external environment, covering most of the human body. It is essential to keep the skin hydrated to maintain its normal function. While the water content of the inner layers of the skin remains relatively constant, adequate hydration is essential for keeping the skin healthy, plump, and radiant. Aiming to achieve and maintain healthy and beautiful skin is a common desire, particularly among women. Hence, cosmetic companies are increasingly focused on developing improved hydrating and moisturizing products to meet the growing demand.

Our Zebrafish-based Moisturization & Hydration Efficacy Evaluation

• Gene expression

Hyaluronic acid is known for its excellent moisturizing properties. In the synthesis of hyaluronic acid (HA), human hyaluronan synthases (HAS) are a crucial class of enzymes, with HAS3 playing a significant role in the production of epidermal hyaluronan.

Aquaporin (AQP) is a protein that is widely distributed in various tissue parts of organisms and plays a crucial role in the process of water metabolism. Among different types of aquaporins, Aquaporin 3 (AQP3) is the most important one in the skin. It acts as a water and glycerol transport protein in the plasma membrane of the basal and acanthotic layers of the epidermis, promoting skin hydration.

At Creative Biogene, we detect the expression of Has3 and Aqp3 genes to evaluate the moisturization & hydration efficacy of your cosmetics.

• Zebrafish tail area

The epidermis of zebrafish exhibits a unique osmotic pressure tolerance range. If the osmotic pressure tolerance range is exceeded, it can lead to dehydration, ultimately causing the tail area to shrink. At Creative Biogene, we have established a stable method for inducing dehydration in zebrafish using NaCl solution. By incubating your cosmetic product with zebrafish, we can capture high-resolution images to analyze the zebrafish tail area, which enables us to evaluate the moisturization & hydration efficacy of your cosmetic product.

Creative Biogene Zebrafish Platform is a renowned company that specializes in offering comprehensive cosmetic efficacy evaluation services. We have been in the cosmetic industry for several years and have amassed vast knowledge and experience in the cosmetics field, making us the go-to experts for all your needs. If you are interested in our services, please do not hesitate to contact us at any time or submit an inquiry directly. We are looking forward to cooperating with you.

For research use only. Not intended for any clinical use.