Renal Protection Evaluation for Dietary Supplements

Are you looking for a reputable company that provides scientific evaluation of health claims for your dietary supplements? Creative Biogene Zebrafish Platform is your unique choice. We specialize in offering zebrafish-based scientific evaluation of renal protection to dietary supplements industry players. By conducting comprehensive studies and employing rational analysis methods, we ensure the delivery of reliable data that help our clients discover the relationship between the dietary supplements and renal health.

Kidney is an essential organ of the human body, responsible for removing waste products from the blood and maintaining a balance of acid-base and osmotic pressure within the body. Chronic kidney disease (CKD) is a non-communicable disease that affects a significant proportion of the global population, with varying degrees of severity. Hence, there is a growing interest in dietary supplements that claim to protect the kidney. Scientific evaluation is a crucial step in verifying the health claim of dietary supplements, thereby ensuring their credibility and gaining the trust of consumers.

Our Zebrafish-based Scientific Evaluation of Renal Protection

Aristolochic acid is a plant secondary metabolite. Taking large amounts of aristolochic acid can directly damage renal tubular epithelial cells, especially proximal renal tubular epithelial cells, leading to cell necrosis or apoptosis.

At Creative Biogene, we utilize aristolochic acid to induce kidney morphological dysfunction. We divide zebrafish into three groups, including a vehicle control group, a model group, and a dietary supplement group. After adding your dietary supplements for a period of time, we evaluate the renal protective effect of your dietary supplements by the incidence of renal edema and glomerular filtration rate in zebrafish. Details are as follows.

Group SettingVehicle control group
Model group
Dietary supplement group
Modeling MethodAristolochic acid induces kidney morphological dysfunction in zebrafish
Analysis MethodMicroscopy observation
Data DeliveryEndpoints:
  • Incidence of renal edema
  • Glomerular filtration rate
Written report available on request

If you are interested in our services, please feel free to contact us at any time or submit an inquiry to us directly. We are looking forward to cooperating with you.

For research use only. Not intended for any clinical use.

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