Weight Management Evaluation

Are you looking for a reliable partner to evaluate the potential of your dietary supplements in weight management? Creative Biogene Zebrafish Platform is the best choice for you. Our extensive expertise in zebrafish-based research enables us to offer top-notch scientific evaluation of weight management. With our expertise, you can be sure that your products will receive the necessary validation to help them stand out in a competitive marketplace.

Obesity is a global epidemic that is associated with a higher risk of a multiplicity of devastating diseases. Dietary supplements, particularly those with thermogenic, lipotropic, or satiety properties, are used by many consumers to support dietary and lifestyle programs for weight management. Despite the multiple presence of dietary supplements for weight management, the dietary supplements industry is consistently exploring novel ingredients for weight management purposes that offer improved outcomes.

Zebrafish is a well-known model organism to study human disease, for their organs and tissues are similar to those of humans in terms of both structure and function. In addition, zebrafish has been reported to be an excellent model for lipid metabolism, and a useful animal model for the analysis of anti-obesity effects of natural products in a shorter time compared with rodents. Hence, zebrafish is being progressively utilized as model of human obesity and obesity-related diseases.

Our Zebrafish-based Scientific Evaluation of Weight Management

At Creative Biogene Zebrafish Platform, we use egg yolk powder to induce an obesity model in zebrafish. We divide the zebrafish into three groups, including: a control group, a model group, and a dietary supplement group. To observe the alterations in fat content within the intestine and blood vessels, we stain the zebrafish with oil red O.

Group SettingVehicle control group
Model group
Dietary supplement group
Modeling MethodEgg yolk powder induces obesity in zebrafish
Analysis MethodOil red O staining
Data DeliveryImages of oil red O staining
Written report available on request

Example Data

Fig. 1 Zebrafish stained with oil red O and visualized under a microscopeFig. 1 Zebrafish stained with oil red O and visualized under a microscope

If you are interested in our services, please do not hesitate to contact us at any time or submit an inquiry to us directly. We are looking forward to cooperating with you.

Reference

  1. Xiao, Y.; et al. Comprehensive evaluation of the composition of Mingshan Laochuancha green tea and demonstration of hypolipidemic activity in a zebrafish obesity model. RSC advances. 2019, 9(70): 41269-41279.

For research use only. Not intended for any clinical use.

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