Memory Improvement Evaluation

If you are looking to gain a deeper understanding of the relationship between your dietary supplements/probiotics and memory improvement, the Creative Biogene Zebrafish Platform can provide you with a suite of comprehensive scientific evaluations. Our team is committed to providing you with accurate and reliable information, so you can make informed decisions about your dietary supplements.

Memory loss can be a frustrating and overwhelming experience, often hindering one's ability to perform daily tasks. It refers to the consistent issues in recollecting things that you were able to remember earlier. It can be either temporary, caused by stress or lack of sleep, or permanent, caused by neurological disorders such as Alzheimer's disease. As we age, some forms of memory loss become more likely to happen, making it important to take proactive steps to support brain health.

In recent times, there has been a growing interest in using dietary supplements/probiotics to fortify memory. If you are looking to develop a product to address the concerns of individuals looking to improve their memory, our services can help you gain insight into the relationship between your products and memory improvement. We can help you discover the most effective ingredients for memory improvement and explore innovative formulations. In addition, we can also help your products stand out in the competitive marketplace.

Our Zebrafish-based Scientific Evaluation of Memory Improvement

Creative Biogene Zebrafish Platform has employed the utilization of aluminum chloride as an important tool to induce memory loss in zebrafish. In order to thoroughly evaluate the efficacy of your dietary supplements or probiotics, we divide zebrafish into three groups, including a vehicle control group, a model group, and a dietary supplement/probiotic group. Following the administration of your dietary supplements/probiotics, we carry out a series of behavioral tests to observe their ability to respond to external light and dark stimuli. Additionally, we also test the activity of acetylcholinesterase in the zebrafish to further evaluate the efficacy of your dietary supplement/probiotics for memory improvement.

Group SettingVehicle control group
Model group
Dietary supplement/Probiotic group
Modeling MethodAlCl3 induces memory loss in zebrafish.
Analysis Method
  • Behavioral system
  • ELISA kit
Data DeliveryEndpoints:
  • Speed changes in zebrafish per minute
  • AChE activity
Written report available on request

Example Data

Fig. 1 Behavioral changes in the zebrafish larvae per minute.Fig. 1 Behavioral changes in the zebrafish larvae per minute.

Fig. 2 Change in the swimming speedFig. 2 Change in the swimming speed

Fig. 3 The inhibitory effect of ZBP on the changes in acetylcholinesterase and acetylcholine caused by AlCl3. (A) Changes in the AChE activity; (B) Changes in the ACh content.Fig. 3 The inhibitory effect of ZBP on the changes in acetylcholinesterase and acetylcholine caused by AlCl3. (A) Changes in the AChE activity; (B) Changes in the ACh content.

If you are interested in our services, please do not hesitate to contact us at any time or submit an inquiry to us directly. We are looking forward to cooperating with you.

Reference

  1. Chen, H.; et al. The therapeutic effect of Zhenbao pills on behavioral changes in zebrafish caused by aluminum chloride. Biomedicine & Pharmacotherapy. 2023, 160: 114399.

For research use only. Not intended for any clinical use.

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