Blood Glucose Management Evaluation

If you are looking for a reliable partner to accelerate the process of getting your dietary supplements to market? Creative Biogene is the perfect choice for you! We offer cutting-edge services in the scientific evaluation of blood glucose management that can help you gather the data you need to move your product forward. With our expertise in zebrafish and dietary supplements, you can trust that you'll receive accurate and reliable results to discover the relationship between your products and blood glucose. Don't let the research process hold you back - try out Creative Biogene's services now!"

Diabetes is a chronic metabolic disease that is characterized by high blood glucose levels. This disease is becoming increasingly common due to the changes in lifestyle and economic development. It has now become a significant public health problem in countries worldwide. To better understand this disease and its complications, researchers have been using zebrafish as a model organism. The zebrafish pancreas has a structure, function, and regulation of glucose metabolism that is highly consistent with those of mammals. This makes it a valuable tool for studying different types of diabetes and screening dietary supplements or drugs. Zebrafish exhibits sustained hyperglycemia under sugar load conditions and can be induced to develop hyperglycemia resembling human type 2 diabetes using a high-sugar and high-fat diet.

Fig. 1 The wild type of zebrafish (Danio rerio)

Our Zebrafish-based Scientific Evaluation of Blood Glucose Management

At Creative Biogene, we divide the zebrafish into three groups, including: a vehicle control group, a model group, and a dietary supplement group. Then, we use high sugar and high fat diet for modeling purpose. After adding your dietary supplements, we detect the blood glucose level using a blood glucose meter to evaluate their potential in blood glucose management. Details are as follows.

Fig. 2 Effect of treatment (single dose) orally with Hancornia speciosa Gomes in glucose of zebrafish

Creative Biogene is a professional organization specializing in dietary supplements health claims studies, aiming to deliver professional health claims studies services to our clients around the world. If you are interested in our services, please feel free to contact us at any time or submit an inquiry to us directly. We are looking forward to cooperating with you.

References

1. HIDAYAH, N.; et al. Development of induced diabetic model using zebrafish. 2018.
2. Tomazi, R.; et al. Hypoglycemic activity of aqueous extract of latex from Hancornia speciosa Gomes: a study in zebrafish and in silico. Pharmaceuticals. 2021, 14(9): 856.

For research use only. Not intended for any clinical use.