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Scientific Solutions
Drug Safety Evaluation in Adult Zebrafish
Accelerate early toxicity screening with a cost-effective, high-throughput vertebrate model that integrates behavioral, histopathological, and biochemical endpoints to identify neurotoxic and systemic risks before advancing to mammalian studies.
Preclinical Safety Services
Gene Expression and Signaling Studies in Zebrafish
Validate molecular targets, elucidate signaling cascades, and quantify gene expression changes in a high-throughput in vivo vertebrate model. Our zebrafish platform enables rapid, cost-effective assessment of inflammation, muscle health, and disease pathways with direct translational relevance.
Molecular Mechanism Research Services
Accelerate Drug Discovery with Clinically Relevant Zebrafish Models
Our Zebrafish Disease Model Construction Service provides end-to-end support for creating genetically defined models that recapitulate human disease pathology.
Zebrafish Disease Model Construction Service
Accelerate Lead Prioritization with Whole-Organism In Vivo Efficacy Data
The zebrafish (Danio rerio) model bridges the gap between in vitro assays and mammalian studies, offering a whole-organism context that reveals systemic drug effects – from target engagement to behavioral and metabolic outcomes.
Pharmacodynamic Evaluation In Zebrafish
Accelerate Translational Research with Predictive Zebrafish Efficacy Models
Zebrafish (Danio rerio) have emerged as a powerful vertebrate model for preclinical efficacy testing, offering a unique combination of optical transparency, high fecundity, and genetic homology to humans—approximately 70% of human disease genes have a zebrafish orthologue.
Zebrafish Disease Model Service
Discover Neuroactive Compounds with Whole-Organism Behavioral Readouts
The larval zebrafish (Danio rerio) has become a powerful vertebrate model for identifying compounds that modulate nervous system activity.
In Vivo Neuroactivity Screening
High-Throughput Screening for Skin-Whitening & Pigment-Modulating Compounds
Cosmetic ingredient developers and pharmaceutical teams face a common challenge: cell-based assays lack whole-organism context, yet mammalian models are slow and costly for early-stage screening.
Zebrafish Pigmentation Screening Service
Liver Toxicity Screening Service
Drug-induced liver injury (DILI) remains a leading cause of attrition during both early and late-stage drug development, as well as post-marketing withdrawals.
In Vivo Zebrafish Hepatotoxicity Screening
Parkinson's Disease Model & Efficacy Evaluation
Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by the selective loss of dopaminergic neurons in the brain.
Zebrafish Disease Model
Quantify Pigment Modulation with Integrated In Vitro and Zebrafish Models
Our service provides quantitative readouts of melanocyte differentiation and melanin production, critical for evaluating compounds targeting pigmentation pathways.
Melanocyte Differentiation & Melanin Detection
Visualize Neuronal Activity in Real Time
In vivo calcium imaging enables direct visualization of neuronal activity by recording fluorescence changes from genetically encoded calcium indicators (GECIs) such as GCaMP6s.
In Vivo Calcium Imaging & Neural Circuit Analysis
Zebrafish Developmental Toxicity Evaluation Service
Identifying developmental toxicity risks early in drug and chemical development is critical to avoid costly late-stage failures.
Preclinical Toxicology Screening
Zebrafish Disease Modeling: Accelerate Target Validation and Drug Discovery
Zebrafish (Danio rerio) have become a cornerstone of preclinical drug discovery, offering a unique balance between the genetic tractability of invertebrate models and the physiological complexity of rodents.
Translational Model Services
Zebrafish Embryo Developmental Toxicity Assay
Each year, thousands of compounds must be screened for developmental toxicity during pharmaceutical and chemical development.
Whole-Organism Developmental Toxicity Screening
Zebrafish Retinal Toxicity Assessment
Retinal toxicity remains a leading cause of late-stage attrition in ophthalmic drug development. Standard rodent models, though predictive, are slow and resource-intensive, often delaying candidate selection.
In Vivo Ocular Safety Screening